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Generic Medicine Savings Calculator

Enter the brand and generic prices you have been quoted to see your real cost per tablet, per month and per year – and exactly how much switching could save.

Reviewed by John Creek [M.B.B.S] · Updated 8 Oct 2026
Calculate my savings ↓
Quick answerTo compare brand and generic fairly, work out the cost per tablet (pack price ÷ tablets in the pack), multiply by how many you take, and add shipping for online orders. Approved generics contain the same active ingredient, strength and dosage form as the brand and must meet bioequivalence standards, so the saving is usually the main difference.
What you compareCost per tablet, month and year
CurrenciesUSD · GBP · AUD · EUR · INR
IncludesShipping per order
Generic standardSame ingredient, strength, form

Brand vs generic cost comparison

Use your own quoted prices. Everything is calculated in your browser – nothing is stored or sent.

Quick fill:SildenafilDaily tadalafilLevothyroxineOlmesartanValacyclovirDutasteride
Brand
Generic
Use 0.5 for half a tablet, or your average for as-needed use (e.g. 0.3 for about twice a week).
Shipping cost × orders per year is added to the generic total.

Estimates only, based on the prices you enter. Always compare the same active ingredient, strength and dosage form, and confirm any switch with your prescriber or pharmacist.

How the generic savings calculator works

Medicine prices are hard to compare because pack sizes differ. The calculator turns every price into a cost per tablet or unit, then scales it to your real use:

  1. Cost per unit = pack price ÷ units in the pack.
  2. Monthly cost = cost per unit × units per day × 30.4 days.
  3. Yearly cost = monthly cost × 12, plus shipping × orders per year for the generic.
  4. Saving = brand yearly cost − generic yearly cost, also shown per month and over 5 years.

What must match between a brand and its generic

Must be the sameCan be different
Active ingredientColour, shape and size of the tablet
Strength (for example, 20 mg)Inactive ingredients such as fillers and dyes
Dosage form (tablet, capsule, cream, eye drop)Packaging and pack size
Route (by mouth, on the skin)Brand name and manufacturer
Bioequivalence – same amount absorbed within strict limitsPrice

The FDA requires this for approved generics in the US, and regulators such as the MHRA in the UK and the TGA in Australia apply similar standards. The WHO builds its Model List of Essential Medicines around generic names for the same reason.

Common brand → generic swaps on MyRxBox

BrandActive ingredientGeneric or branded-generic options
ViagraSildenafilCenforce, Fildena, Kamagra, Caverta
CialisTadalafilVidalista, Tadaflo, Megalis, Tazzle
LevitraVardenafilVilitra, Valif
SynthroidLevothyroxineEltroxin (25–125 mcg)
BenicarOlmesartanOlmecip 20, Olmecip 40
Benicar HCT · Azor · TribenzorOlmesartan combinationsOlmecip H, Olmecip AM, Olmecip Trio
MedrolMethylprednisolonePredmet
ZithromaxAzithromycinAzipro, Azicip
ValtrexValacyclovirValcivir
TamifluOseltamivirFluvir, Antiflu
DiflucanFluconazoleFluka, Zocon DT
AvodartDutasterideDutas, Duprost
ZofranOndansetronEmeset
SingulairMontelukastMontair
LatisseBimatoprost 0.03%Careprost, Bimat
Retin-ATretinoinRetino-A
SoolantraIvermectin cream 1%Ivermectin cream 1%
XenicalOrlistatSlim Trim 120

See the full list in our generic medicine equivalents directory.

When to take extra care switching

Some medicines have a narrow therapeutic index, meaning small changes in blood levels matter. Examples include levothyroxine, warfarin and some anti-epileptic drugs. You can still use generics, but stay on one consistent product where possible and ask your doctor to recheck levels about 6–8 weeks after any change. Combination products, extended-release forms and inhalers also need careful matching – check the exact strength and release type, not just the ingredient name.

More ways to cut your medicine costs

  • Compare per tablet, not per pack. A bigger pack is often cheaper per unit.
  • Order a longer supply where your prescription allows, to reduce shipping per tablet.
  • Check current offers such as discount codes on larger orders and free-shipping thresholds.
  • Ask about combination tablets – one combined tablet can cost less than two separate ones.
  • Ask your pharmacist whether a lower-cost equivalent strength or form is suitable.
  • Never cut a tablet unless it is scored and your pharmacist confirms it is safe to split.

Read 15 ways to lower medication costs and how to compare Rx prices before you pay.

Popular generic medicines

Compare prices and pack sizes on each product page, then enter them in the calculator above.

SildenafilCenforce 100 mgGeneric for Viagra.Compare price →TadalafilVidalista 20 mgGeneric for Cialis.Compare price →TadalafilTadaflo 5 mgDaily low-dose tadalafil.Compare price →LevothyroxineEltroxin 50 mcgThyroid hormone replacement.Compare price →OlmesartanOlmecip 20 mgGeneric for Benicar.Compare price →SpironolactoneAldactone 25 mgBlood pressure and fluid control.Compare price →ValacyclovirValcivir 1000 mgGeneric for Valtrex.Compare price →DutasterideDutas 0.5 mgGeneric for Avodart.Compare price →AzithromycinAzipro 500 mgGeneric for Zithromax.Compare price →BimatoprostCareprost 0.03%Same ingredient as Latisse.Compare price →TretinoinRetino-A 0.05%Same ingredient as Retin-A.Compare price →Ivermectin 1%Ivermectin creamSame ingredient as Soolantra.Compare price →

Related guides on saving money

Generic equivalents directoryFind the generic for your brandMedicine price indexCurrent per-tablet pricesBrand vs generic medicinesSame ingredient, different price?Rx price comparison 2026How to compare before you pay15 ways to cut medicine costsDiscounts and savingsGoodRx alternativeAnother way to compareMedicine name decoderBrand vs generic, strength and formHow to compare medicationsIngredient, strength, safety, priceCommon medicines and ingredientsA–Z guidePrescription strength explainedWhat 5, 10, 20, 50 and 100 mg meanMedicine expiry date checkRead EXP, MFG and batch infoBefore you buy medicine online7 checks that save troubleIs an online pharmacy legit?12 warning signsAffordable Rx online – USAOrdering from the USOnline pharmacy – UKOrdering from the UKOnline pharmacy – AustraliaOrdering from Australia

Generic savings FAQs

How much can I save with generic medicines?

It depends on the medicine and where you buy it. Savings are often largest for medicines whose patents have expired and that are made by many manufacturers. Enter your own quotes in the calculator for an accurate figure.

Is a generic exactly the same as the brand?

The active ingredient, strength, dosage form and route must match, and regulators require bioequivalence. Inactive ingredients, colour and shape can differ.

Why are generics cheaper?

Generic makers do not repeat the original discovery research and large clinical trials, and competition between several manufacturers pushes prices down.

Why does my generic look different from last time?

Different manufacturers make the same generic. Check the label shows the same active ingredient and strength, and ask your pharmacist if you are unsure.

Should I switch levothyroxine to a generic?

You can, but stay on one product consistently and ask your doctor to recheck your TSH about 6 to 8 weeks after any change.

How do I compare different pack sizes fairly?

Compare the cost per tablet or unit, which the calculator works out automatically, and include shipping for online orders.

How do I calculate cost for as-needed medicines?

Enter your average use per day. For example, if you take a tablet about twice a week, enter 0.3 units per day.

Does the calculator store my prices?

No. Everything is calculated in your browser and nothing is saved or sent.

Is a branded generic the same as a generic?

A branded generic, such as Cenforce or Eltroxin, is a generic version sold under the manufacturer’s own brand name. It contains the same active ingredient as the original brand.

Can I split tablets to save money?

Only if the tablet is scored and your pharmacist confirms it is safe to split. Many tablets, including extended-release forms, must not be cut.

Know your generic? Check the price.

See current per-tablet prices across our full range.

Medicine price indexAll free health tools

Sources & official guidelines

Disclaimer: Results are estimates based on the prices you enter. MyRxBox tools are not medical or financial advice. Always confirm any change of medicine with your prescriber or pharmacist.
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